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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK17
All Species:
24.85
Human Site:
S491
Identified Species:
49.7
UniProt:
Q00537
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00537
NP_002586.2
523
59582
S491
P
E
S
V
S
I
F
S
L
K
E
I
Q
L
Q
Chimpanzee
Pan troglodytes
XP_001146785
513
58578
Y472
E
E
A
M
K
H
V
Y
F
R
S
L
G
P
R
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
L454
D
T
T
S
I
F
A
L
K
E
I
Q
L
Q
K
Dog
Lupus familis
XP_539731
541
61618
S509
P
E
S
V
S
I
F
S
L
K
E
I
Q
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0D0
523
59488
S491
P
E
S
V
S
I
F
S
L
K
E
I
Q
L
Q
Rat
Rattus norvegicus
O35831
523
59414
S491
P
E
S
V
S
I
F
S
L
K
E
I
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510894
523
59528
S491
P
E
S
V
S
I
F
S
L
K
E
I
Q
L
Q
Chicken
Gallus gallus
XP_416161
516
58803
Y472
E
E
A
M
K
H
A
Y
F
R
S
L
G
T
R
Frog
Xenopus laevis
Q6DJM7
435
49211
T403
S
D
M
S
S
I
F
T
V
P
N
V
K
L
Q
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
K387
R
D
T
V
S
I
F
K
V
P
G
V
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
L263
L
D
P
A
G
L
D
L
L
S
K
M
L
R
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
L263
L
D
P
D
G
V
D
L
L
S
K
M
L
L
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
67.3
94.6
N.A.
98.6
96.3
N.A.
98.4
95.7
43.4
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.8
80.1
95.1
N.A.
99.8
97.7
N.A.
99.4
97.1
56.9
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
100
6.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
20
100
N.A.
100
100
N.A.
100
40
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
31.5
N.A.
31.5
N.A.
N.A.
Protein Similarity:
N.A.
44.5
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
0
17
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
0
9
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
17
59
0
0
0
0
0
0
0
9
42
0
0
0
9
% E
% Phe:
0
0
0
0
0
9
59
0
17
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
9
0
17
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
59
0
0
0
0
9
42
0
0
0
% I
% Lys:
0
0
0
0
17
0
0
9
9
42
17
0
9
0
9
% K
% Leu:
17
0
0
0
0
9
0
25
59
0
0
17
25
67
0
% L
% Met:
0
0
9
17
0
0
0
0
0
0
0
17
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
42
0
17
0
0
0
0
0
0
17
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
42
9
50
% Q
% Arg:
9
0
0
0
0
0
0
0
0
17
0
0
9
9
17
% R
% Ser:
9
0
42
17
59
0
0
42
0
17
17
0
0
0
0
% S
% Thr:
0
9
17
0
0
0
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
50
0
9
9
0
17
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _